Hormone excretion patterns in anovulatory infertility.

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Hormone excretion patterns in anovulatory infertility.

BEFORE embarking upon a discussion of anovulatory infertility, it is necessary to define a physiologically normal menstrual cycle and to review our present knowledge of the hormonal changes that occur. In humans a 'normal' cycle has a mean length of 28 32 days+0 6 days (SD = 5 41 days), ovulation occurs and there must be normal corpus luteum function. Recent reviews of the normal changes in the...

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Management of anovulatory infertility.

Anovulatory subfertility is a heterogeneous condition with various underlying causes, which should be identified with appropriate history taking, physical examination and relevant investigations. Optimisation of body weight is essential in either underweight, overweight or obese individuals. Women with hypogonadotrophic anovulation can be treated with pulsatile gonadotrophin-releasing hormone t...

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Evidence • Systematic review of RCTs of antiestrogens in PCOS1: -In 3 RCTs (N = 133) that examined clomiphene (50 to 250 mg/d, 1 to 5 cycles) versus placebo, the pregnancy rate was higher with clomiphene (20% vs 3%); the number needed to treat (NNT) was 6. Live births and miscarriages were not reported. -Limitations: small sample, variable dosing and number of cycles, high dropout rate, poor ad...

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Obesity and anovulatory infertility: A review

This global overweight and obesity epidemics has become one of the largest public health problem worldwide and is increasingly more common among women in reproductive age. Along with the prevalence of overweight women, there is an increase in women with anovulatory infertility. Thus, we carried out a bibliographic research in the PubMed, Lilacs and SciELO databases, using the combinations in Po...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1972

ISSN: 0032-5473

DOI: 10.1136/pgmj.48.555.5